Natural products synthesis is one of major research interests of our group. Complex molecule synthesis not only serves for the further biological and medicinal studies, but provides new question and promotes the innovation of synthetic methods. Our group is interested in development of simple, novel methods and strategies that enable C-C, C-heteroatom bond formations and functionalization of unsaturated carbon-carbon bonds, and finally these new developed methods would be used in the total synthesis of highly functionalized natural products.